癫痫杂志

癫痫杂志

癫痫合并阻塞性睡眠呼吸暂停综合征相关危险因素的研究进展

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癫痫是多种原因导致的脑部神经元高度同步化异常放电的临床综合征。阻塞性睡眠呼吸暂停综合征(Obstructive sleep apnea syndrome,OSAS)是一种病因不明的睡眠呼吸疾病,临床表现有夜间睡眠打鼾伴呼吸暂停和白天嗜睡,呼吸暂停可引起反复发作的夜间低氧血症和高碳酸血症。越来越多研究证明,癫痫患者中 OSAS 的发病率远远高于正常人群,两病共患具有治疗难及预后差的特点。夜间反复呼吸暂停会导致睡眠片段化和睡眠剥夺,可能是导致癫痫患者难治的原因之一。现对癫痫合并 OSAS 的相关危险因素进行总结。

关键词: 癫痫; 阻塞性睡眠呼吸暂停综合征; 相关性; 危险因素

引用本文: 王芬, 丁勇民, 罗新明, 张明. 癫痫合并阻塞性睡眠呼吸暂停综合征相关危险因素的研究进展. 癫痫杂志, 2018, 4(4): 340-343. doi: 10.7507/2096-0247.20180056 复制

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